Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND)

Observational Study

Get in touch about this study

What is the study about?

COMPASS-ND is Canada’s largest dementia study that aims to better understand various cognitive conditions in the aging population. For the first time, this study will integrate a wide range of measures (e.g. clinical, neuropsychological, imaging data) to address the causes, diagnosis, management, treatment, and prevention of these conditions.


Eligibility–Who can participate?

Participants must:

  • Be 50-90 years of age (or 60-90 years of age if in the healthy volunteer, subjective cognitive impairment, mild cognitive impairment (MCI), or vascular MCI groups)
  • Have memory conditions (i.e., subjective cognitive impairment, mild cognitive impairment (MCI), subcortical ischemic vascular MCI, mild Alzheimer’s disease, dementia of mixed etiology, Lewy Body disease, Parkinson’s dementia/MCI and frontotemporal dementia), or be a healthy volunteer
  • Have a study partner who must have regular contact with the participant (at least one interaction per week). The study partner will be asked to provide information and accompany the patient to all visits

Time requirement:

  • 4-6 visits over 3 months, with follow-up visits at 1 and 2 years
  • Annual telephone checks will be conducted and the baseline procedures may be repeated after 2 years
  • Visits will include cognitive testing, questionnaires, biosample collection, MRI, neurological and physical exams

TDRA investigator

Drs. Sandra Black, Carmela Tartaglia

More information

TDRA Site:


Address: 3560 Bathurst St, North York, ON M6A 2E1

Sunnybrook Health Sciences Centre

Address: 2075 Bayview Ave, Toronto, ON M4N 3M5

University Health Network (UHN)-Toronto Western Hospital

Address: 399 Bathurst Street, Toronto ON M5T 2S8

Age Group:

, , , , , ,

Target Population:

, , , , , , , , ,

Do you have questions about research studies you saw on this page? Please contact


The listing of a study on the Toronto Dementia Network (TDN) is for informational purposes only. The safety, efficacy or scientific validity of the studies listed here have not been evaluated by The Alzheimer Society of Toronto (AST) or the Toronto Dementia Research Alliance (TDRA). The TDRA is an academic coalition among the University of Toronto and four memory clinics across Toronto at Baycrest, the Centre for Addiction and Mental Health, Sunnybrook Health Sciences Centre, and the University Health Network. The information collected will be kept and guarded by TDRA. Choosing to participate in a study is an important personal decision. Before you participate in a study, you should make sure you understand the risks and potential benefits and discuss all options with your health care provider(s).