Home-Based Cognitive Remediation and Transcranial Direct Current Stimulation to Enhance Cognition in Persons with Mild Cognitive Impairment and Late Life Depression

Interventional Study

Get in touch about this study

What is the study about?

This study looks at whether cognitive remediation (performing computer exercises that target memory, attention and processing speed) along with transcranial direct current stimulation (a low-intensity, painless form of brain stimulation) done at home can help prevent dementia in people with mild cognitive impairment and/or a history of depression.


Eligibility- Who can participate?

Participants must:

  • Be 60 years of age or older
  • Have a diagnosis of mild cognitive impairment and/or a history of depression
  • Have a study partner that is willing to help with the brain stimulation on a daily basis at home


Time requirement

Treatment: Up to 2-hour sessions at-home, 5 days a week, over a total of 8 weeks

Cognitive and mood assessments: At baseline and follow-ups every 6 months or 1 year over a maximum of 2 years


TDRA study investigator

Dr. Tarek Rajji


More information



TDRA Site:

Participate from home

Age Group:

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Target Population:


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The listing of a study on the Toronto Dementia Network (TDN) is for informational purposes only. The safety, efficacy or scientific validity of the studies listed here have not been evaluated by The Alzheimer Society of Toronto (AST) or the Toronto Dementia Research Alliance (TDRA). The TDRA is an academic coalition among the University of Toronto and four memory clinics across Toronto at Baycrest, the Centre for Addiction and Mental Health, Sunnybrook Health Sciences Centre, and the University Health Network. The information collected will be kept and guarded by TDRA. Choosing to participate in a study is an important personal decision. Before you participate in a study, you should make sure you understand the risks and potential benefits and discuss all options with your health care provider(s).