Intranasal Oxytocin for Frontotemporal Dementia (FOXY)

Interventional Study

Get in touch about this study

What is the study about?

This study is investigating the effects of oxytocin, a natural hormone in the body, on behavioural symptoms in people with frontotemporal dementia (FTD), compared to placebo.


Eligibility- Who can participate?

Participants must:

  • Be 30 to 80 years of age
  • Have a diagnosis of frontotemporal dementia (FTD) or known FTD-causing genetic mutations
  • Have current symptoms of social apathy/indifference
  • Have a study partner


Time requirement

5 visits over 6 months.


TDRA Study Investigators

Sunnybrook: Dr. Mario Masellis

Toronto Western Hospital: Dr. Carmela Tartaglia


More information

TDRA Site:

Sunnybrook Health Sciences Centre

Address: 2075 Bayview Ave, Toronto, ON M4N 3M5

University Health Network (UHN)-Toronto Western Hospital

Address: 399 Bathurst Street, Toronto ON M5T 2S8

Age Group:

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Target Population:

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The listing of a study on the Toronto Dementia Network (TDN) is for informational purposes only. The safety, efficacy or scientific validity of the studies listed here have not been evaluated by The Alzheimer Society of Toronto (AST) or the Toronto Dementia Research Alliance (TDRA). The TDRA is an academic coalition among the University of Toronto and four memory clinics across Toronto at Baycrest, the Centre for Addiction and Mental Health, Sunnybrook Health Sciences Centre, and the University Health Network. The information collected will be kept and guarded by TDRA. Choosing to participate in a study is an important personal decision. Before you participate in a study, you should make sure you understand the risks and potential benefits and discuss all options with your health care provider(s).