What is the study about?
The study examines the safety and effectiveness of antidepressant medications for older adults with difficult-to-treat depression, looking at medication side effects, overall well-being and falls.
Eligibility- Who can participate?
- be 60 years of age or older
- be diagnosed with Current Major Depressive Disorder, single or recurrent
- have not responded to two or more anti-depressant treatment trials of recommended dose and length (approximately 12 weeks)
10 bi-weekly phone calls and 5 in-person visits (or 10 phone calls if unable to attend in person) over 17 months
TDRA study investigators
Drs. Benoit Mulsant, Krista Lanctot
BaycrestSt. Michael’s Hospital
Address: 209 Victoria St, Toronto, ON M5B 1T8Sunnybrook Health Sciences CentreUniversity Health Network (UHN)-Toronto General Hospital