What is the study about?
The study examines the safety and effectiveness of antidepressant medications for older adults with difficult-to-treat depression, looking at medication side effects, overall well-being and falls.
Eligibility- Who can participate?
- be 60 years of age or older
- be diagnosed with Current Major Depressive Disorder, single or recurrent
- have not responded to two or more anti-depressant treatment trials of recommended dose and length (approximately 12 weeks)
10 bi-weekly phone calls and 5 in-person visits (or 10 phone calls if unable to attend in person) over 17 months
TDRA study investigators
Drs. Benoit Mulsant, Krista Lanctot
BaycrestCentre for Addiction and Mental Health (CAMH)
Address: 1001 Queen St W, Toronto, ON M6J 1H4St. Michael’s Hospital
Address: 209 Victoria St, Toronto, ON M5B 1T8Sunnybrook Health Sciences CentreUniversity Health Network (UHN)-Toronto General Hospital