Telmisartan vs. Perindopril in Mild-Moderate Alzheimer’s Disease Patients (SARTAN-AD) trial

Interventional Study

Get in touch about this study

What is the study about?

The SARTAN-AD study is comparing the effects of two approved medications for high blood pressure – Telmisartan and Perindopril – on their ability to maintain brain function in people with mild to moderate Alzheimer’s disease.


Eligibility–Who can participate?

Participants must:

  • Be 50 years of age or older
  • Have a diagnosis of Alzheimer’s disease
  • Have had a previous MRI or CT brain scan
  • Have a study partner who can come to all study visits

Time requirement:

  • Screening visit
    • In-person—3 hours
    • Phone/Email – 10 min
    • In-Person MRI -1 hour
  • Baseline visit (in person)—4 hours
  • Week 2 follow-up (phone or in person)—15-30 mins
  • Month 1 follow-up (in person)—1 hour
  • Month 3 follow-up (phone or in person)—1 hour
  • Month 6 follow-up (in person)—4 hours
  • Month 9 follow-up (phone or in person)—1 hour
  • Month 12 follow-up (in person)—5 hours

TDRA investigator

Drs. Sandra Black and Sanjeev Kumar


More information

TDRA Site:

Centre for Addiction and Mental Health (CAMH)

Address: 1001 Queen St W, Toronto, ON M6J 1H4

Sunnybrook Health Sciences Centre

Address: 2075 Bayview Ave, Toronto, ON M4N 3M5

Age Group:

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Target Population:

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The listing of a study on the Toronto Dementia Network (TDN) is for informational purposes only. The safety, efficacy or scientific validity of the studies listed here have not been evaluated by The Alzheimer Society of Toronto (AST) or the Toronto Dementia Research Alliance (TDRA). The TDRA is an academic coalition among the University of Toronto and four memory clinics across Toronto at Baycrest, the Centre for Addiction and Mental Health, Sunnybrook Health Sciences Centre, and the University Health Network. The information collected will be kept and guarded by TDRA. Choosing to participate in a study is an important personal decision. Before you participate in a study, you should make sure you understand the risks and potential benefits and discuss all options with your health care provider(s).