Enhancing Frontal Lobes Plasticity and Function in Patients with Mild Cognitive Impairment (PAS-MCI)

What is the study about?

This study is assessing the use of a novel brain stimulation technique called Transcranial Magnetic Stimulation to determine if it can improve memory and thinking processes in people diagnosed with Mild Cognitive Impairment. We are conducting this experiment to assess whether TMS can strengthen the connection between different cells in the frontal area of the brain that is especially relevant to attention and memory in Mild Cognitive Impairment, a condition that often precedes dementia.

Eligibility–Who can participate?

Participants must:

• Be 60 years of age or older
• Have a diagnosis of mild cognitive impairment or be a healthy volunteer

Time requirement:

Participants will undergo treatment sessions that range from 1.5 to 3 hours at CAMH, 5 days a week, over a total of 2 weeks. In addition, participants will complete clinical and cognitive assessments at baseline, after treatment, and again 3 weeks later.

TDRA investigator

Dr. Tarek Rajji

More information

https://clinicaltrials.gov/ct2/show/NCT04583215

TDRA Site:

Centre for Addiction and Mental Health (CAMH),

Address: 1001 Queen St W, Toronto, ON M6J 1H4

Age Group:

60 - 64, 65 - 69, 70 - 80, 81 - 85, 86 - 90, 91+

Target Population:

Healthy volunteer, Mild cognitive impairment