Brain-Eye Amyloid Memory (BEAM) Study

What is the study about?

This study is investigating whether measurements of the eye can be used with other tests to detect dementia earlier. By comparing the results of non-invasive tests similar to those done in an eye doctor’s office with established tests of cognition, magnetic resonance imaging (MRI) and a positron emission tomography (PET) scan, researchers can look for links between changes in parts of the eye in dementia.

 

Eligibility–Who can participate?

Participants must be:

• 50-90 years of age or older

• Have a diagnosis of Alzheimer’s disease, mild cognitive impairment (MCI), or vascular cognitive impairment (VCI), Lewy Body Spectrum disorders, or be a healthy volunteer

 

Time requirement:

4-5 visits over 4 months. The visits will include undergoing brain imaging (MRI, PET), cognitive testing, gait and balance assessments, eye-imaging, cognitive and functional questionnaires, and taking blood samples.

 

TDRA investigator

Drs. Sandra Black, Sanjeev Kumar, Corinne Fischer, Howard Chertkow and Carmela Tartaglia

 

More information

https://clinicaltrials.gov/ct2/show/NCT02524405

 

Video
Advances in Dementia Research Webinar- Listen to Dr. Sandra Black (Principal Investigator) discuss the BEAM study in further detail: https://youtu.be/U1PVnwg6Kzs

TDRA Site:

Baycrest

Address: 3560 Bathurst St, North York, ON M6A 2E1

Centre for Addiction and Mental Health (CAMH)

Address: 1001 Queen St W, Toronto, ON M6J 1H4

St. Michael’s Hospital

Address: 209 Victoria St, Toronto, ON M5B 1T8

Sunnybrook Health Sciences Centre

Address: 2075 Bayview Ave, Toronto, ON M4N 3M5

University Health Network (UHN)-Toronto Western Hospital

Address: 399 Bathurst Street, Toronto ON M5T 2S8

Age Group:

50 - 54, 55 - 59, 60 - 64, 65 - 69, 70 - 80, 81 - 85, 86 - 90

Target Population:

Alzheimer’s disease, Dementia with Lewy bodies (DLB), Healthy volunteer, Lewy Body Dementia (LBD), Mild cognitive impairment, Vascular Cognitive Impairment