What is the study about?
This study is investigating whether measurements of the eye can be used with other tests to detect dementia earlier. By comparing the results of non-invasive tests similar to those done in an eye doctor’s office with established tests of cognition, magnetic resonance imaging (MRI) and a positron emission tomography (PET) scan, researchers can look for links between changes in parts of the eye in dementia.
Eligibility–Who can participate?
Participants must be:
- 50-90 years of age or older
- Have a diagnosis of Alzheimer’s disease, mild cognitive impairment (MCI), or vascular cognitive impairment (VCI), Lewy Body Spectrum disorders, or be a healthy volunteer
4-5 visits over 4 months. The visits will include undergoing brain imaging (MRI, PET), cognitive testing, gait and balance assessments, eye-imaging, cognitive and functional questionnaires, and taking blood samples.
Drs. Sandra Black, Sanjeev Kumar, Corinne Fischer, Howard Chertkow and Carmela Tartaglia
BaycrestCentre for Addiction and Mental Health (CAMH)
Address: 1001 Queen St W, Toronto, ON M6J 1H4St. Michael’s Hospital
Address: 209 Victoria St, Toronto, ON M5B 1T8Sunnybrook Health Sciences CentreUniversity Health Network (UHN)-Toronto Western Hospital