Enhancing Frontal Lobes Plasticity and Function in Patients with Mild Cognitive Impairment (PAS-MCI)

Interventional Study

Get in touch about this study

What is the study about?

This study is assessing the use of a novel brain stimulation technique called Transcranial Magnetic Stimulation to determine if it can improve memory and thinking processes in people diagnosed with Mild Cognitive Impairment. We are conducting this experiment to assess whether TMS can strengthen the connection between different cells in the frontal area of the brain that is especially relevant to attention and memory in Mild Cognitive Impairment, a condition that often precedes dementia.


Eligibility–Who can participate?

Participants must:

  • Be 60 years of age or older
  • Have a diagnosis of mild cognitive impairment or be a healthy volunteer

Time requirement:

Participants will undergo treatment sessions that range from 1.5 to 3 hours at CAMH, 5 days a week, over a total of 2 weeks. In addition, participants will complete clinical and cognitive assessments at baseline, after treatment, and again 3 weeks later.


TDRA investigator

Dr. Tarek Rajji


More information


Advances in Dementia Research Webinar- Listen to Dr. Tarek Rajji (Principal Investigator) discuss the PAS-MCI study in further detail:  https://youtu.be/SChLxrZp1jA 
TDRA Site:

Centre for Addiction and Mental Health (CAMH)

Address: 1001 Queen St W, Toronto, ON M6J 1H4

Age Group:

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Target Population:


Do you have questions about research studies you saw on this page? Please contact tdra@utoronto.ca


The listing of a study on the Toronto Dementia Network (TDN) is for informational purposes only. The safety, efficacy or scientific validity of the studies listed here have not been evaluated by The Alzheimer Society of Toronto (AST) or the Toronto Dementia Research Alliance (TDRA). The TDRA is an academic coalition among the University of Toronto and four memory clinics across Toronto at Baycrest, the Centre for Addiction and Mental Health, Sunnybrook Health Sciences Centre, and the University Health Network. The information collected will be kept and guarded by TDRA. Choosing to participate in a study is an important personal decision. Before you participate in a study, you should make sure you understand the risks and potential benefits and discuss all options with your health care provider(s).