Photobiomodulation (light therapy) for amnestic mild cognitive impairment (aMCI)

Interventional Study

Get in touch about this study

What is the study about?

This study is looking at using a form of non-invasive light therapy called photobiomodulation as a treatment for amnestic Mild Cognitive Impairment (aMCI), which is an early stage of Alzheimer’s disease. The study will look at the effect of the light therapy on your thinking abilities, quality of life, and the powerhouse of cells (the mitochondria).


Eligibility- Who can participate?

Participants must:

  • Be 50 years of age or older
  • Have a diagnosis of Mild Cognitive Impairment (MCI)


Time requirement

The entire study can take 10 to 12 weeks, and consist of:


  • Screening visit to assess eligibility
  • Baseline visit (2-3 sessions) to complete cognitive testing, blood test, and brain MRI/MRS
  • At home treatments for 20 minutes per day, 6 days a week, for 6 weeks
  • Post treatment visit (2-3 sessions) to complete the same tasks as the baseline visit


TDRA study investigator

Dr. Corinne Fischer, Dr. Tom Schweizer


More information


Advances in Dementia Research Webinar- Listen to Dr. Neda Rashidi-Ranjbar discuss this  study in further detail:

TDRA Site:

St. Michael’s Hospital

Address: 209 Victoria St, Toronto, ON M5B 1T8

Age Group:

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Target Population:

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The listing of a study on the Toronto Dementia Network (TDN) is for informational purposes only. The safety, efficacy or scientific validity of the studies listed here have not been evaluated by The Alzheimer Society of Toronto (AST) or the Toronto Dementia Research Alliance (TDRA). The TDRA is an academic coalition among the University of Toronto and four memory clinics across Toronto at Baycrest, the Centre for Addiction and Mental Health, Sunnybrook Health Sciences Centre, and the University Health Network. The information collected will be kept and guarded by TDRA. Choosing to participate in a study is an important personal decision. Before you participate in a study, you should make sure you understand the risks and potential benefits and discuss all options with your health care provider(s).